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Heart Disease & the Health Benefits of Green Tea

Coronary Artery Disease
An elevation in the amount of free radicals in the arteries is a key event in many forms of cardiovascular disease. The latest research shows that green tea catechins inhibit the enzymes involved in the production of free radicals in the endothelial lining of the arteries. The arterial endothelium is a one-cell thick lining that serves as the interface between the bloodstream and the wall of the artery where plaques can form. By protecting the endothelium from free radical damage, green tea catechins help prevent the development of cardiovascular disease.

-www.whfoods.org


Inhibits Atherosclerosis
Green tea has been shown to effectively lower risk of atherosclerosis by lowering LDL cholesterol, triglycerides, lipid peroxides (free radicals that damage LDL cholesterol and other lipids or fats) and fibrinogen (a protein in the blood involved in the formation of blood clots), while improving the ratio of LDL (bad) to HDL (good) cholesterol.

Special Benefits for Persons with High Triglycerides

Green tea may offer special heart-protective benefits for persons with high triglycerides, suggests a laboratory study, published in the February 2005 issue of the Journal of Nutrition.

A series of experiments revealed that the mix of catechins naturally found in green tea dose-dependently inhibit the activity of pancreatic lipase, the enzyme secreted by the pancreas that digests fat. As a result, the rate at which the body breaks down of fats into triglycerides, and the rise of triglyceride levels in the bloodstream that occurs after meals, is greatly slowed.

Since a large rise in blood levels of triglycerides after a meal is a significant risk factor for coronary heart disease, drinking a cup or two of green tea along with your meals is a good idea, especially if your triglyceride levels are higher than normal.

-Journal of Nutrition, February 2005


Protects the Heart in Patients with Acute Cardiovascular Disease
The primary catechin in green tea, EGCG (epigallocatechin-3-gallate) confers such powerful protection that it can help prevent the death of heart muscle cells following ischemia/reperfusion injury. Ischemia is the medical term for a restriction in blood supply and therefore in oxygen and nutrients. When circulation is restored, oxidative damage occurs, and this is referred to as reperfusion injury.

EGCG prevents heart muscle damage by blocking the activation of inflammation-related compounds (including NF-kappa-B and STAT-1) that play a critical role in promoting the oxidative damage that kills heart cells in reperfusion injury. Researchers believe EGCG can be used to help minimize damage in patients with acute coronary artery disease.

-www.whfoods.org


Minimizes Damage and Speeds Recovery after a Heart Attack
Research conducted over the last several years by Dr. Anastasis Stephanou and his team at the UK's Institute of Child Health and published in the FASEB Journal, the journal of the Federation of Experimental Biology and the Journal of Cellular and Molecular Medicine has focused on EGCG's ability to block the action of the protein, STAT-1. Normally activated in cells after a heart attack or stroke, STAT-1 plays a major role in inducing cell death.

Not only does green tea minimize heart cell death after a heart attack or stroke, ECGC also appears to speed up heart cells' recovery from damage, allowing the tissues to recover more quickly and alleviating damage to organs.

Dr. Stephanou, a molecular biologist, noted: "We're extremely encouraged by these findings and hope to implement them in the clinical setting to minimize cell death activation in patients with acute coronary heart disease."

-www.whfoods.org


Tea Consumption Linked to Reduced Risk of Myocardial Infarction
Drinking more than three cups of tea daily appears to reduce a patient's risk of myocardial infarction (MI), according to a longitudinal, population-based study. Researchers analyzed the tea consumption of 4,807 men and women ages 55 and older. They found that the risk of MI among those who consumed more than three cups of tea daily was about half that of non-tea drinkers.

-RN, Jun 2002


Tea May Reduce a Person's Risk of Dying After a Heart Attack
According to a recent report, drinking lots of tea may reduce a person's risk of dying after a heart attack. Scientists found that participants who drank the most tea were the least likely to die during the three or four years after a heart attack.

-Medical Update, January 2002


After a Heart Attack, Tea Reduces the Risk of Dying by 44 Percent
Better to be deprived of food for three days than tea for one," says a Chinese proverb. Research is showing it may just be true. Last week Dr. Kenneth Mukamal of Boston's Beth Israel Deaconess Medical Center reported that out of 900 heart-attack patients, those who drank two or more cups a day reduced their risks of dying over the next 3.8 years by 44 percent.

-Newsweek, May 20, 2002


Green Tea Consumption Results in Reduction of Cancer and Cardiovascular Disease
The epidemiological study with 8552 general residents in Japan revealed: drinking green tea (1) decreased relative risk of cancer incidence by 43~46%. (2) decreased relative risk of death from cardiovascular disease by 28%. (3) the benefits of decreased risks were for those consuming (green tea diet) over 10 cups a day, compared with those consuming below 3 cups

--Biofactors. 2000;13(1-4):49-54


Relation Between Green Tea Consumption and the Severity of Coronary Atherosclerosis 
Study on 512 Japanese patients found: benefits in men but not in women, odds ratios of significant stenosis for consumption of green tea (green tea diet) 4 or more cups per day was 0.4 (95% confidence interval 0.2-0.9), as compared with a consumption of green tea one cup per day or less 

-Ann Epidemiol 2000 Aug;10(6):401-8


Chinese Green Tea Lowers Cholesterol Level Through an Increase in Fecal Lipid Excretion
The study demonstrated green tea significantly lowered the serum cholesterol level. This benefit is achieved by increasing fecal bile acids and cholesterol excretion

-Life Sci 2000;66(5):411-23  


Green Tea Consumption and Serum Lipid Profiles
Study of cross-sectional data on 1,306 males in Japan found: serum total cholesterol levels were inversely related to the consumption of green tea. Adjusted mean concentrations of total cholesterol were 8 mg/dl lower in men drinking (green tea diet) 9 or more cups of green tea per day than in those consuming 0 ~ 2 cups per day. 3 cups per day was the minimum for the green tea benefit. 

-Prev Med. 1992 Jul;21(4):526-31


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